Publications

HRA Pharma has collaborated on a number of scientific publications in the areas of women’s health and endocrinology – whether through scientific cooperation or sponsorship.

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Publications

HRA Pharma has collaborated on a number of scientific publications in the areas of women’s health and endocrinology – whether through scientific cooperation or sponsorship.

An inactivating mutation within the first extracellular loop of the thyrotropin receptor impedes normal posttranslational maturation of the extracellular domain.
Sura-Trueba S, Aumas C, Carre A, Durif S, Leger J, Polak M, de Roux N.Endocrinology. 2009 Feb;150(2):1043-50
M909 plays a key role in the activation of the progesterone receptor and also in the high potency of 13-ethyl progestins
Isabelle Petit-Topin, Nathalie Turque, Jérôme Fagart, André Ulmann, Erin Gainer and Marie-Edith Rafestin-OblinMol Pharmacol. Mol Pharmacol. 2009 Jun;75(6):1317-24. Epub 2009 Mar 16.
Molecular mechanisms of thyroid dysgenesis.
Polak M, Sura-Trueba S, Chauty A, Szinnai G, Carré A, Castanet M.Horm Res. 2004;62 Suppl 3:14-21. Review.
Polymorphic length of FOXE1 alanine stretch: evidence for genetic susceptibility to thyroid dysgenesis.
Carré A, Castanet M, Sura-Trueba S, Szinnai G, Van Vliet G, Trochet D, Amiel J, Léger J, Czernichow P, Scotet V, Polak M. Hum Genet. 2007 Dec;122(5):467-76.
Sodium/iodide symporter (NIS) gene expression is the limiting step for the onset of thyroid function in the human fetus.
Szinnai G, Lacroix L, Carré A, Guimiot F, Talbot M, Martinovic J, Delezoide, AL, Vekemans M, Michiels S, Caillou B, Schlumberger M, Bidart JM, Polak M.J Clin Endocrinol Metab. 2007 Jan;92(1):70-6.
Busiah K, Drunat S, Vaivre-Douret L,et al. Neuropsychological dysfunction and neurodevelopmental defects associated with genetic changes in infants with neonatal diabetes mellitus: a prospective cohort study.
Lancet Diabetes Endocrinol. 2013 ; 3:199-207
Bonnefond A, Lomberk G, Buttar N, Busiah K, et al. Disruption of a novel Kruppel-like transcription factor p300-regulated pathway for insulin biosynthesis revealed by studies of the c.-331 INS mutation found in neonatal diabetes mellitus.
J Biol Chem. 2011; 286:28414-24
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